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01) and more relaxed behaviour when entering the examination room (p=0.02). There were very few adverse events, and treated animals were not sedated. This study indicated a beneficial treatment effect of dexmedetomidine gel in alleviation of canine fear and anxiety during minor veterinary or husbandry procedures in the clinic environment in dogs previously reported to suffer from fear and anxiety during veterinary visits. Both dexmedetomidine gel doses studied were effective, and no clinical safety concerns were noticed for either dose.