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A short protocol of apheresis showed excellent results without superiority of IA over PP for antibodies with an initial MFI 3000. For antibodies showing MFI ≥2000 after four sessions, the residual MFI predicted the effectiveness of four additional sessions. Monitoring the MFI of anti-HLA antibodies before and during apheresis protocol can guide physicians in the selection of apheresis technique and the number of sessions to be performed. Monitoring the MFI of anti-HLA antibodies before and during apheresis protocol can guide physic