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istically significant difference in quality of life at 6 months. These findings support potentially basing decisions about treatment on other end points. ClinicalTrials.gov Identifier NCT02391337 and clinicaltrialsregister.eu Identifier 2015-005043-13. ClinicalTrials.gov Identifier NCT02391337 and clinicaltrialsregister.eu Identifier 2015-005043-13. The number of cancer survivors who develop new cancers is projected to increase, but comprehensive data on the risk of subsequent primary cancers (SPCs) among survivors of adult-onset cancer