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With this validated, the model can be used with much higher confidence to explore the fluid and particle dynamics within the device. This work shows the importance of selecting the correct turbulence modelling approach and boundary conditions to obtain good agreement with PIV data for the flow-field exiting the device. With this validated, the model can be used with much higher confidence to explore the fluid and particle dynamics within the device.Vertebrate cardiac muscle generates progressively larger systolic force when the en