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The microtubule-associated protein tau (MAPT) H1 haplotype is the strongest genetic risk factor for corticobasal degeneration (CBD). However, the specific H1 subhaplotype association is not well defined, and it is not clear whether any MAPT haplotypes influence severity of tau pathology or clinical presentation in CBD. Therefore, in the current study we examined 230 neuropathologically confirmed CBD cases and 1312 controls in order to assess associations of MAPT haplotypes with risk of CBD, severity of tau pathology (measured as semi-quant

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Most studies on hydrophobic surfaces processed by lasers rely on the use of pico- or femtosecond lasers. However, in industrial application, the fabrication methods using pico- or femtosecond lasers have the disadvantages of high cost and low efficiency In this study, we tried to fabricate hydrophobic surfaces using a high-power general-purpose diode laser. We have fabricated various micro/nano hierarchical structures for aluminum (Al5052) surface using laser groove processing technology. The surface of laser ablated micro structure is dec