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Severe Combined Immunodeficiency (SCID) is an inherited group of rare, life-threatening disorders due to the defect in T cell development and function. Clinical manifestations are characterised by recurrent and severe bacterial, viral, and fungal opportunistic infections that start from early infancy period. Haematopoietic stem cell transplantation (HSCT) is the treatment of choice. The pattern of inheritance of SCID may be X-linked or autosomal recessive. Though the diagnosis of SCID is usually established by flow cytometry

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How to Diagnose and Repair UPVC Door Issues Upvc doors are extremely popular in modern buildings due to their energy efficiency and long-lasting durability. As with all fixtures the doors of upvc can experience issues that require repair to ensure their proper functioning. Plastic filler with a low shrinkage can be used to repair minor cracks. Hinges that aren't aligned properly can also be realigned to restore their function. Cracks and Scratches Scratches and scuffs on uPVC doors may appear minor, but they can affect t