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Stage IV rectal cancer occurs in 25% of patients and locoregional control of primary tumor is usually poorly considered, since priority is the treatment of metastatic disease. This study evaluates impact of neoadjuvant chemoradiation followed by surgery (nCHRTS) vs. upfront surgery on locoregional control and overall survival in stage IV rectal cancer. All patients diagnosed with stage IV rectal carcinoma between 2009 and 2019, undergone elective surgery at the National Cancer Institute of Milan (Italy), were included. Propensity score-ba

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Seven strong suggestion sub-items were included with APPROPRIATE Statement and formed the last RIGHT-TCM. The group hopes that the RIGHT-TCM may assist TCM guide designers in stating guidelines, help log editors and peer reviewers when it comes to TCM guideline reports, and help medical care practitioners realize and implement a TCM guide. This article will present its background, development, tips and explanation.Despite the broad applications of dry anaerobic digestion (AD), a number of fundamen