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An amendment to this paper has been published and can be accessed via the original article.Background Smoking plays a key role in the development of tuberculosis (T infection and is also a predictor of poor TB treatment prognosis and outcomes. The current study was conducted to determine the prevalence of smoking and to assess the effects of smoking on treatment outcomes among TB patients. Methods A multi-center retrospective study design was used to collect data from TB patients in four different states of Malaysia, namely Pen