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06% vs. 66.67%, P = 0.003). The subgroup analysis revealed that ECIRS was more efficacious than Mini-PCNL for complex renal calculi with medium and high S-ReSC scores (P = 0.002). A nonsignificant but relatively lower postoperative complication rate was noted in the ECIRS group (7.5 vs. 16.0%, P = 0.12). With the exception of postoperative hospitalization days (P less then 0.001), significant difference was not detected between the two groups for other procedure-related information. ECIRS in the GMSV position is an effective and safe trea