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This allowed the optimization of this IM spectrometer for best analytical overall performance. While ion desolvation is less efficient at RP, the transportation of ions is much more efficient, resulting in intensity enhancement and an elevated quantity of oligomer ions. Whenever deciding between AP and RP IR-MALDI, a trade-off between power and resolving power has got to be considered. Right here, the lower area mobility of peptide ions was initially measured and weighed against research values