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are propagated to the highest trophic levels likely depends on responses of individual prey taxa and their relative susceptibility to predation. This article is protected by copyright. All rights reserved.First, we read with interest and we thank Dr. Tomoyuki Kawada for his thoughtful letter (1) about our recent paper titled "Depression and risk of Cognitive Dysfunctions in Amyotrophic Lateral Sclerosis". This article is protected by copyright. All rights reserved.Leigh syndrome is a clinically and radiologically heterogeneous condition w