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0% vs. 40.2%, P = 0.005) in the comparison with the control group, but no significant differences in hepatic toxicities were observed. In conclusion, Simultaneous administration of silymarin is a potential effective supplementation for reducing toxicities in mCRC patients undergoing first-line 53 FOLFIRI plus bevacizumab, especially in diarrhea and nausea.Background Most U.S. patient and health care provider surveys with regard to nasal allergy treatments were conducted before sublingual immunotherapy (SLIT)-tablets and allergy immunot