https://www.selleckchem.com/pr....oducts/crenolanib-cp
01) and duration (p less then 0.001) of spike-wave discharges (SWDs), while injection of antagonist reduced amplitude (p less then 0.001) and duration (p less then 0.01) of SWDs in the somatosensory cortex of epileptic rats. The high expression of GluR1 in the somatosensory cortex of epileptic rats suggests the role of AMPA receptors consisting of the GluR1 subunit in the development of absence seizures. The modulatory effects AMPA receptors on the feature of SWDs suggest the potential of AMPA receptors antagonists as a the
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