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89; 95% CI 0.82, 0.96). Similarly, higher overall n-6 PUFA concentrations were also associated with a reduced AF risk (HR per SD increment 0.93; 95% CI 0.87, 1.0. Although no significant overall associations were observed for any individual n-3 PUFAs, higher circulating concentrations of DHA (226n-3) and EPA (205n-3) were associated with a decreased AF risk in blacks and Hispanics (DHA only) but not whites or Chinese Americans. In a multiethnic cohort of individuals free of baseline cardiovascular disease, higher plasma concentrations