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74 [0.39-1.46]), or 3 months of DAPT (HR, 1.00 [0.54-1.86]) followed by aspirin monotherapy. Except for de-escalation of DAPT to aspirin monotherapy after 3-months (HR, 0.75 [0.43-1.20]), de-escalation to P2Y12 inhibitor monotherapy after 1-month (HR, 0.28 [0.10-0.83]), or 3-months (HR, 0.57 [0.33-0.98]) were associated with significant decrease in total bleeding events. There were no significant differences in terms of ischemic endpoints among different DAPT strategies. CONCLUSION Early de-escalation of DAPT (1-3 months) to monothera