https://www.selleckchem.com/pr....oducts/Dapagliflozin
A detailed and systematic quantum-chemical calculation has been performed with high-level density functional theory (DFT) to analyze the electrostatic interaction of methanesulfonic acid (CH3SO3H), also known as MSA, with pre-formed clusters of sulfuric acid (H2SO4) molecules in ambient conditions. Both MSA and H2SO4 are considered as atmospheric molecules that might play active roles in aerosol formation. The interactions between MSA and H2SO4 clusters lead to the formation of MSA···(H2SO4) n (n = 2, 3) complexes stabilized by th

https://www.selleckchem.com/pr....oducts/Sunitinib-Mal
The degree of repair was histologically scored after 8 weeks. WNT3a was successfully loaded on exosomes and resulted in activation of WNT signalling in vitro. In vivo, recombinant WNT3a failed to activate WNT signalling in cartilage, whereas a single administration of WNT3a loaded exosomes activated canonical WNT signalling for at least one week, and eight weeks later, improved the repair of osteochondral defects. WNT3a assembled on exosomes, is efficiently delivered into cartilage and contributes to the healing of ost