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It has been demonstrated that vitamin D (Vit D) included in diets offers a beneficial effect by improving innate immune responses in chickens. However, its mechanisms of action and the effect on immunosuppressive pathogens, such as infectious bursal disease virus, are not yet known. In the present study, we have studied the immunomodulatory effect of Vit D on the innate immune response in 3 cell lines fibroblast cells (DF-1), macrophages (HD11), and B cells (DT-4 infected with IBDV (intermediate vaccine) at 2 multiplicity of infectio
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