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The introduction of vaccinations against hepatitis B into the preventive vaccination calendar has led to a significant decrease in the incidence of viral hepatitis B among the population under 18 years of age. The goal is to analyze the effect of viral hepatitis in the Republic of Kazakhstan. Our studies of a 5-year cross-section showed that the incidence of chronic viral hepatitis B tends to decline. So, if the number of CHB diseases in 2012 was at the level of 35.4 cases per 100 thousand population, then in 2016 this figure decreased by