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C]-l-lactate to identify hepatic pyruvate carboxylase activity in vivo under fed and fasted conditions. were assessed in vitro in a 3 Telsa MR scanner. Two groups of healthy rats (fasted vs. fed) had been ready for in vivo studies. Each rat had been anesthetized and intravenously injected with 60-mM hyperpolarized [1- C]-l-lactate had been calculated as 67.8 s and 40.0%, respectively. [1- C]aspartate had been produced frourable pyruvate carboxylase/pyruvate dehydrogenase chemical
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