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All rights reserved.The hepatitis C virus primarily infects the liver but is additionally in a position to infect and replicate various other human body compartments by generating an extra-hepatic reservoir that will influence the persistence associated with illness after transplantation. It's unknown whether antiviral medicines impact the viral extra-hepatic sites. We evaluated the power of pegylated/interferon + ribavirin and sofosbuvir + ribavirin to clear the herpes