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Puppies had been arbitrarily allocated into 1 of 4 teams (OVX-E0, dogs that did not get any estrogen replacement therapy; OVX-E0.5, dogs that obtained 0.15 mg/kg of estradiol; OVX-E1, dogs that obtained 0.3 mg/kg of estradiol; and OVX-E2, dogs that received 0.6 mg/kg of estradiol); dogs had been assessed clinically for 12 months; and contact radiographic and histopathologic examinations of the TMJ were performed right after euthanasia. RESULTS Radiographic examination of the TMJ in the OVX-E0 gr

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