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The data indicates that the aquaporin 3 is an important cell membrane channel to mediate arsenic uptake and contributes to the arsenic-induced autophagy.Mass-wasting of ocean island volcanoes is a well-documented phenomenon. Massive flank collapses may imply tens to hundreds of km3 and generate mega-tsunamis. However, the causal links between this large-scale, low-frequency instability, and the time-space evolution of magma storage, crystal fractionation/accumulation, lithospheric assimilation, and partial melting remains unclear. This p