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Medication For Autism and ADHD Many children and adults with autism take psychotropic medication. Certain of these medications may aid in reducing the irritability and severe disruptive behavior that can occur in ADHD. The use of medications for ADHD can significantly improve autism's core symptoms and reduce the severity of impulsivity, inattention, as well as hyperactivity. They can also help reduce problematic behaviors such as aggression and self-inju