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The modern-day receptors are derived from those contained in germs that lived over 320 million years back. The pathogens represent more host adapted members of the bacterial lineages and might have facets that permit them to own strong relationship because of the mucosal epithelial cells, thus most likely reside in another type of niche compared to the commensal people in the microbial lineage. The bacterial pathogens ordinarily lead a commensal lifestyle which presents d