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Our findings are expected to inspire the construction of smart supramolecular systems based on dynamic coordinative metal centers. The purpose of this study was to investigate the association and impact of TMEM50A on RH genes activity and function. SMP1 is located on chromosome 1p36.11 in the RH gene locus, between the RHD and RHCE gene, where its position may be linked to RH haplotypes and contribute to selective pressures regarding certain RH haplotypes. TMEM50A is encoded by the SMP1 located in the intergenic region of RH, its influen
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