https://www.selleckchem.com/pr....oducts/Irinotecan-cp
Dual targeted therapy in HER2-positive breast cancer cells with the combination of carbon dots/HER3 siRNA and Trastuzumab resulted in enhanced antitumor activity, which overcomes the resistance to Trastuzumab monotherapy. Herein, we have developed branched polyethylenimine functionalized carbon dots (BP-CDs) nanocarriers, which exhibited efficient GFP gene delivery and expression. The positively charged BP-CDs allowed for an effective nucleic acid binding and displayed a high-efficient small interfering RNA (siRNA)-mediated de