https://www.selleckchem.com/pr....oducts/nec-1s-7-cl-o
Further, the mouse recombinant protein CXCL4 was used to culture normal mouse CD4+ T cells in vitro. Our finding indicated that the recombinant protein CXCL4 promoted the percentage of mouse CD25+FOXP3+Treg cells and enhanced the phosphorylation of STAT5 in mouse CD4+ T cells in a dose-dependent manner. However, these effects were significantly reversed by the STAT5 inhibitor (p less then .001). Conclusion our findings not only indicated the function and signalling pathway of CXCL4 in CD4+ T cells but also provided novel insi
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