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d RHD cases will experience one of the major complications of RHD within 8 years supporting the need for programmes to eradicate RHD. Cardiovascular disease is the leading cause of death in chronic kidney disease (CKD) patients, although the pathophysiological mechanisms are not fully studied. This study aimed to determine whether CKD could adversely affect subclinical left heart function in a sample of the general population without cardiac disease. We examined 1158 participants who voluntarily underwent extensive cardiovascular exam