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miR-335 also inhibited the migration and invasion of cancer cells. MAP3K2 was shown to be the target gene of miR-335 and the silencing of MAP3K2 was seen to mimic the growth inhibitory effect of miR-335. The overexpression of MAP3K2 reversed the growth inhibition in miR-335 mimics-transfected BC cells. Conclusion miR-335 has growth inhibitory effect against BC and negatively regulates the cell migration and invasion along with enhancement of chemo-sensitivity of cancer cells.Purpose To investigate the possible association between materna

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