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Thus, based on the current and previous results, we propose that multisite Cdk1 phosphorylation is critical for the formation of Ska-Ndc80 macro-complexes that are essential for chromosome segregation.Myeloid differentiation protein 1 (MD1) is exerted an anti-arrhythmic effect in obese mice. Therefore, we sought to clarify whether MD1 can alter the electrophysiological remodeling of cardiac myocytes from obese mice by regulating voltage-gated potassium current and calcium current. MD1 knock-out (KO) and wild type (WT) mice were given a
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