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In addition, we formalize our problem as an integer linear program problem and solve it using the PuLP package and the standard CPLEX algorithm. Our exploration of several candidate operons reveals that our new method provides more optimal results than the results from the heuristic approach, and is significantly faster. The software and data accompanying this paper are available under the GPLv3 and CC0 license respectively on https//github.com/nguyenngochuy91/Relevant-Operon. The software and data accompanying this paper are available und
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