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An AR share ended up being identified when a drug caused hypothermia in crazy kind mice which was diminished in mice lacking all four ARs (quadruple knockout, QKO). Instead, an adenosinergic result was identified if a drug potentiated adenosine-induced hypothermia. Four medicines (dipyridamole, nimodipine, cilostazol, cyclosporin A) increased the hypothermia brought on by adenosine. Dipyridamole and nimodipine most likely achieved this b
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