https://www.selleckchem.com/products/rbn-2397.html
BACKGROUND In vertebrate genomes, CpG sites can be clustered into CpG islands, and the amount of methylation in a CpG island can change due to gene regulation processes. Thus, single regulatory events can simultaneously change the methylation states of many CpG sites within a CpG island. This should be taken into account when quantifying the amount of change in methylation, for example in form of a branch length in a phylogeny of cell types. RESULTS We propose a probabilistic model (the IWE-SSE model) of methylation dynamics that accou
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