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60, 95% CI 1.16, 18.28). This was most apparent for women with higher radiation doses to the contralateral breast. Among young female survivors of breast cancer, we found some evidence suggesting that having an interval pregnancy could increase a woman's risk of CBC following RT for a first breast cancer. While sampling variability precludes strong interpretations, these findings suggest a role for pregnancy and hormonal factors in radiation-associated CBC. Among young female survivors of breast cancer, we found some evidence suggesting