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Colorectal cancer (CRC) is a very common cancerous tumor of intestinal tract that has high incidence and mortality prices. Correct prognosis prediction of CRC clients is crucial to reduce the death and disease burden. In this study, we comprehensively analyzed the gene appearance and methylation data of CRC examples through the Cancer Genome Atlas (TCGA). Differential appearance genes (DEGs) and methylation CpGs (DMCs) in tumor areas in contrast to adjacent regular areas of CRC were initia