https://www.selleckchem.com/pr....oducts/2-3-cgamp.htm
16, 95% CI 1.03~1.30, p = 0.02), but not total symptomatic KOA (RR = 0.84, 95% CI 0.65~1.08, p = 0.18). Stratified analyses suggested that MetS was independently associated with an increased risk of KOA in women (RR = 1.23, 95% CI 1.03~1.47, p = 0.02), but not in men (RR = 0.90, 95% CI 0.70~1.14, p = 0.37). Current evidence from prospective cohort studies did not support MetS was an independent risk factor of overall KOA in general population. However, MetS may be associated with an increased risk of severe KOA in general population,