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05), but no difference for Rgps levels. Within its limitations, the results of this study show that incremental 3-time application of as a probiotic led to improvements in clinical and biochemical parameters. This protocol can be a useful adjunct to SRP in the non-surgical management of CP. Clinical Trials Registry - India Identifier CTRI/2017/03/008231. Clinical Trials Registry - India Identifier CTRI/2017/03/008231. This study was conducted to determine how the distance of the near insertion points in a vertical mattress suture