https://www.selleckchem.com/pr....oducts/pkc-theta-inh
Refractory chronic cough (RCC) is a debilitating condition for which there are no licensed treatments. Lidocaine is a nonselective inhibitor of voltage-gated sodium channels with potential antitussive effects, but randomized placebo-controlled studies evaluating its efficacy in RCC are lacking. To investigate the efficacy of nebulized lidocaine and lidocaine throat spray versus matched placebos in RCC. This was a randomized, double-blind, double-dummy, placebo-controlled, 3-way crossover study, comparing the effect of single