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for a particular WGS pipeline, which would be useful when interpreting and delivering clinical reports. The current standard of a mean depth of 40X may be sufficient for SNV/indel detection and identification of most CNVs. It would be advisable for clinical scientists to determine the range of sensitivity and PPV for different classes of variants for a particular WGS pipeline, which would be useful when interpreting and delivering clinical reports.Vitamin K2 (menaquinone, MK) is an essential lipid-soluble vitamin with critical roles in