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Clonal haematopoiesis of indeterminant potential (CHIP) increases in frequency with age. The effect of CHIP on the mobilization of autologous CD34+ peripheral blood stem cells (PBSC) has not been reported. This study uses a DNA-based targeted candidate gene approach to identify the presence of somatic mutations in ASXL1, DNMT3A, JAK2, SF3B1, TET2 and TP53 in CD34+ haematopoietic progenitor cell-apheresis products of 96 patients who undergo PBSC mobilization for autologous stem cell transplantation (ASCT). Variants were identified in a sig

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A Guide to Buying a Cheap Double Mattress A double bed that isn't expensive does not mean that it is of low quality. Many reputable sleep companies offer mattresses at less than $1000 for a queen-sized mattress. This is particularly relevant when you shop online, as you will save money by skipping the middleman. Heavy-weight sleepers may discover that cheaper mattresses degrade