https://www.selleckchem.com/pr....oducts/protac-tubuli
Proton-pump inhibitors (PPIs) may increase the risk of kidney stone formation, but the mechanism has not been elucidated. There is a paucity of literature evaluating the effects of PPIs on urinary metabolites and urine pH. We performed a retrospective review of nephrolithiasis patients treated at our institution and compared patients who were taking PPIs to those who werenot at the time of their 24-h urine collections. Hierarchical multivariate linear regression was used to evaluate the independent relationship between
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