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In the US and Germany, decisions leading to high hindrance of others are rejected, whereas in cases of low hindrance, overtaking is preferred. Japanese participants reject decisions, which lead to hindrance of others. To determine if performing repeat tumor molecular profiling in solid malignancies over time can identify new findings that impact clinical care. All patients with a solid malignancy and more than 1 tumor molecular analysis were identified at a single institution. Each test report was examined to identify the genomic altera