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What Happens If ADHD is Left Untreated in Adults? Untreated ADHD can lead to a myriad of issues for adults. These include problems with relationships, work and mental health. Many times, people who suffer from untreated ADHD have low self-esteem as well as a negative view of the world. They may feel like they are failing at home and work. Lack of Focus It is normal to experience difficulty focusing from time to time, especially after a busy day at work or school. If you notice that your ability to