https://www.selleckchem.com/pr....oducts/Temsirolimus.
ught organization. The changes were acute in onset and fluctuating in time. Mice with delirium exhibited decreased expression of key synaptic function-related genes. The behavioral changes induced by anesthesia, surgery, and Intensive Care environment in aged mice are consistent with the clinical features of human delirium, and support the use of this animal model for future mechanistic studies of perioperative delirium. Surgery, anesthesia and Intensive Care environment impaired mouse behaviors that depend on attention, memory, an
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