https://www.selleckchem.com/pr....oducts/pf-06952229.h
BACKGROUND Clinical trials are expensive and often require funding from the pharmaceutical industry (PI). We aimed to compare studies funded by the PI with studies funded by other sources in terms of costs, reported results and strength of evidence. METHODS We searched PubMed for clinical trial reports on metastatic NSCLC published between 2012 and 2017. We divided all studies into two groups studies funded by the PI or by other sources. The primary endpoint was to compare the evidence strength of each group. Secondary endpoints wer

https://www.selleckchem.com/pr....oducts/ro-61-8048.ht
During the development of a multicellular organism, the specification of different cell lineages originates in a small group of pluripotent cells, the epiblasts, formed in the preimplantation embryo. The pluripotent epiblast is protected from premature differentiation until exposure to inductive cues in strictly controlled spatially and temporally organized patterns guiding fetus formation. Epiblasts cultured in vitro are embryonic stem cells (ESCs), which recapitulate the self-renewal and lineage specification properties of their en