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Mammals may use similar regulatory mechanisms because components of the exocytic secretion apparatus and signaling pathways are conserved. © The Author(s) 2020.Thanks to the advancement in science and technology and a significant number of cancer research programs being carried out throughout the world, the prevention, prognosis and treatment of breast cancer are improving with a positive and steady pace. However, a stern thoughtful attention is required for the metastatic breast cancer cases-the deadliest of all types of breast cance