https://www.selleckchem.com/sc....reening-libraries.ht
Finally, an HMM-based postprocessing stage was used to reduce false positives by incorporating the knowledge of transition probabilities between stages into the classification process. The method performance was evaluated using the K-fold (KFCV) and leave-one-out cross-validation (LOOCV) strategies. Main results Using six-bipolar channels, our method achieved a mean kappa and an overall accuracy of 0.71-0.76 and 78.9%-82.4% using the KFCV and LOOCV strategies, respectively. Significance The presented automatic sleep stage scoring met

https://www.selleckchem.com/pr....oducts/bay-2402234.h
Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).PROTACs (PROteolysis TArgeting Chimeras) are bifunctional molecules that target proteins for ubiquitylation by an E3 ligase complex and subsequent degradation by the proteasome. They have emerged as powerful tools to control the levels of specific cellular proteins. We now introduce