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ntly reduce the risk of VTE. However, this protective effect was associated with a significantly increased risk of major bleeding. Apixaban at the appropriate dose can decrease the risk of VTE without increasing the bleeding risk. These findings require validation in larger study cohorts. Malignant obstructive jaundice (MOJ) leads to hyperbilirubinemia and systemic pathophysiological changes. The main clinical treatments for MOJ include radical pancreatoduodenectomy, palliative surgical treatment, and minimally invasive

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Most studies on hydrophobic surfaces processed by lasers rely on the use of pico- or femtosecond lasers. However, in industrial application, the fabrication methods using pico- or femtosecond lasers have the disadvantages of high cost and low efficiency In this study, we tried to fabricate hydrophobic surfaces using a high-power general-purpose diode laser. We have fabricated various micro/nano hierarchical structures for aluminum (Al5052) surface using laser groove processing technology. The surface of laser ablated micro structure is