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We used mass spectrometry-based assays and RNA sequencing to identify both understood ALK, ROS1, RET and NTRK1 rearrangements and novel gene fusions in LARC patients. FusionMap has also been used to find gene fusions. None associated with the ALK, ROS1, RET or NTRK1 gene fusions were detected by mass spectrometry-based assays or RNA sequencing. Three fusion prospects, integrin subunit beta 7 (ITGB7)-ROS1, lamin A/C (LMNA)-NTRK1 and Golgi-associated PDZ an