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When injected into mice, 2-[ At]AAMP exhibited peak accumulation in the tumor at 30min postinjection, and radioactivity levels in the tumor were retained up to 60min. The majority of the radioactivity was rapidly eliminated from the body into urine in an intact form immediately after injection. 2-[ At]AAMP significantly improved the survival of mice (P0.05) without serious side effects. 2-[ At]AAMP showed α-radiation-dependent cellular growth inhibition after it was taken up via LAT1. In addition, 2-[ At]AAMP had a beneficial effect

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